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Human Tumor susceptibility gene 101 protein (aa 1-390)

TSG101 Swiss Prot#

Q99816

TSG101 Protein names

Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)

TSG101 Gene names

TSG101

Organism

Human

TSG101 Entry name

TS101_HUMAN

TSG101 Codon optimized cDNA(gene) Clone

TSG101 Cat #

RPE0162

Tag

TSG101 contains A 6x histidine tag

TSG101 Formulation

Liquid

TSG101 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TSG101 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TSG101 Protein

TSG101 Cat #

PE0162

TSG101 Source

recombinant

TSG101 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TSG101 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TSG101 Activity

N/A

Tag

TSG101 Contains A 6x histidine tag

TSG101 Formulation

Liquid

TSG101 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TSG101 family

Ubiquitin-conjugating enzyme family, UEV subfamily

TSG101 Subcellular locations

Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein.

TSG101 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

TSG101 Sequence

DDBJ

EMBL

GenBank

TSG101 3D structure

ModBase

TSG101 interaction

STRING

TSG101 Proteomic

PRIDE

TSG101 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TSG101 Organism specific

CTD

MGI

TSG101 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TSG101 Gene expression

Bgee

ArrayExpress

Genevestigator

TSG101 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY