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Human ETS-related transcription factor Elf-3 (aa 1-371)

ERT Swiss Prot#

P78545

ERT Protein names

ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelium-specific Ets transcription factor 1) (ESE-1) (Epithelium-restricted Ets protein ESX) (Epithelial-restricted with serine box)

ERT Gene names

ELF3 (ERT) (ESX) (JEN)

Organism

Human

ERT Entry name

ELF3_HUMAN

ERT Codon optimized cDNA(gene) Clone

ERT Cat #

RPE0149

Tag

ERT contains A 6x histidine tag

ERT Formulation

Liquid

ERT Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ERT Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ERT Protein

ERT Cat #

PE0149

ERT Source

recombinant

ERT Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ERT Purity

>90%, as determined by SDS-PAGE under reducing conditions

ERT Activity

N/A

Tag

ERT Contains A 6x histidine tag

ERT Formulation

Liquid

ERT Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ERT family

ETS family

ERT Subcellular locations

Cytoplasm. Nucleus.

ERT FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

ERT Sequence

DDBJ

EMBL

GenBank

ERT 3D structure

ModBase

ERT interaction

STRING

ERT Proteomic

PRIDE

ERT Genome annotation

Ensembl

GeneID

KEGG

UCSC

ERT Organism specific

CTD

MGI

ERT Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ERT Gene expression

Bgee

ArrayExpress

Genevestigator

ERT Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY