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Human Platelet-derived growth factor D (aa 19-370)

IEGF Swiss Prot#

Q9GZP0

IEGF Protein names

Platelet-derived growth factor D (PDGF-D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B) [Cleaved into: Platelet-derived growth factor D, latent form (PDGFD latent form); Platelet-derived growth factor D, receptor-binding form (PDGFD receptor-binding form)]

IEGF Gene names

PDGFD (IEGF) (SCDGFB) (MSTP036) (UNQ1899/PRO4345)

Organism

Human

IEGF Entry name

PDGFD_HUMAN

IEGF Codon optimized cDNA(gene) Clone

IEGF Cat #

RPE0148

Tag

IEGF contains A 6x histidine tag

IEGF Formulation

Liquid

IEGF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IEGF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IEGF Protein

IEGF Cat #

PE0148

IEGF Source

recombinant

IEGF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IEGF Purity

>90%, as determined by SDS-PAGE under reducing conditions

IEGF Activity

N/A

Tag

IEGF Contains A 6x histidine tag

IEGF Formulation

Liquid

IEGF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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IEGF family

PDGF/VEGF growth factor family

IEGF Subcellular locations

Secreted.

IEGF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. Activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet-derived growth factor receptor. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

IEGF Sequence

DDBJ

EMBL

GenBank

IEGF 3D structure

ModBase

IEGF interaction

STRING

IEGF Proteomic

PRIDE

IEGF Genome annotation

Ensembl

GeneID

KEGG

UCSC

IEGF Organism specific

CTD

MGI

IEGF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IEGF Gene expression

Bgee

ArrayExpress

Genevestigator

IEGF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY