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Human Secreted frizzled-related protein 4 (aa 19-346)

FRPHE Swiss Prot#

Q6FHJ7

FRPHE Protein names

Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE)

FRPHE Gene names

SFRP4 (FRPHE)

Organism

Human

FRPHE Entry name

SFRP4_HUMAN

FRPHE Codon optimized cDNA(gene) Clone

FRPHE Cat #

RPE0131

Tag

FRPHE contains A 6x histidine tag

FRPHE Formulation

Liquid

FRPHE Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FRPHE Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FRPHE Protein

FRPHE Cat #

PE0131

FRPHE Source

recombinant

FRPHE Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FRPHE Purity

>90%, as determined by SDS-PAGE under reducing conditions

FRPHE Activity

N/A

Tag

FRPHE Contains A 6x histidine tag

FRPHE Formulation

Liquid

FRPHE Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FRPHE family

Secreted frizzled-related protein (sFRP) family

FRPHE Subcellular locations

Secreted.

FRPHE FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.

FRPHE Sequence

DDBJ

EMBL

GenBank

FRPHE 3D structure

ModBase

FRPHE interaction

STRING

FRPHE Proteomic

PRIDE

FRPHE Genome annotation

Ensembl

GeneID

KEGG

UCSC

FRPHE Organism specific

CTD

MGI

FRPHE Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FRPHE Gene expression

Bgee

ArrayExpress

Genevestigator

FRPHE Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY