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Human Pin2-interacting protein X1 (aa 1-328)

LPTL Swiss Prot#

Q96BK5

LPTL Protein names

Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver-related putative tumor suppressor) (Protein 67-11-3)

LPTL Gene names

PINX1 (LPTL) (LPTS)

Organism

Human

LPTL Entry name

PINX1_HUMAN

LPTL Codon optimized cDNA(gene) Clone

LPTL Cat #

RPE0112

Tag

LPTL contains A 6x histidine tag

LPTL Formulation

Liquid

LPTL Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

LPTL Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant LPTL Protein

LPTL Cat #

PE0112

LPTL Source

recombinant

LPTL Applications

Western Blot, SDS-Page or may be used for other applications determined by user

LPTL Purity

>90%, as determined by SDS-PAGE under reducing conditions

LPTL Activity

N/A

Tag

LPTL Contains A 6x histidine tag

LPTL Formulation

Liquid

LPTL Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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LPTL family

PINX1 family

LPTL Subcellular locations

Nucleus. Nucleus > nucleolus. Chromosome > telomere. Chromosome > centromere > kinetochore.

LPTL FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.

LPTL Sequence

DDBJ

EMBL

GenBank

LPTL 3D structure

ModBase

LPTL interaction

STRING

LPTL Proteomic

PRIDE

LPTL Genome annotation

Ensembl

GeneID

KEGG

UCSC

LPTL Organism specific

CTD

MGI

LPTL Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

LPTL Gene expression

Bgee

ArrayExpress

Genevestigator

LPTL Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY