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Human Aldo-keto reductase family 1 member C2 (aa 1-323)
DDH2 Swiss Prot#
P52895
DDH2 Protein names
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Chlordecone reductase homolog HAKRD)
DDH2 Gene names
AKR1C2 (DDH2)
Organism
Human
DDH2 Entry name
AK1C2_HUMAN
DDH2 Codon optimized cDNA(gene) Clone
DDH2 Cat #
RPE0107
Tag
DDH2 contains A 6x histidine tag
DDH2 Formulation
Liquid
DDH2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
DDH2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant DDH2 Protein
DDH2 Cat #
PE0107
DDH2 Source
recombinant
DDH2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
DDH2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
DDH2 Activity
N/A
Tag
DDH2 Contains A 6x histidine tag
DDH2 Formulation
Liquid
DDH2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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DDH2 family
Aldo/keto reductase family
DDH2 Subcellular locations
Cytoplasm.
DDH2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
DDH2 Sequence
DDBJ EMBL GenBank
DDH2 3D structure
ModBase
DDH2 interaction
STRING
DDH2 Proteomic
PRIDE
DDH2 Genome annotation
Ensembl GeneID KEGG UCSC
DDH2 Organism specific
CTD MGI
DDH2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DDH2 Gene expression
Bgee ArrayExpress Genevestigator
DDH2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY