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Human Prohibitin-2 (aa 2-299)

BAP Swiss Prot#

Q99623

BAP Protein names

Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity) (D-prohibitin)

BAP Gene names

PHB2 (BAP) (REA)

Organism

Human

BAP Entry name

PHB2_HUMAN

BAP Codon optimized cDNA(gene) Clone

BAP Cat #

RPE0093

Tag

BAP contains A 6x histidine tag

BAP Formulation

Liquid

BAP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BAP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BAP Protein

BAP Cat #

PE0093

BAP Source

recombinant

BAP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BAP Purity

>90%, as determined by SDS-PAGE under reducing conditions

BAP Activity

N/A

Tag

BAP Contains A 6x histidine tag

BAP Formulation

Liquid

BAP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BAP family

Prohibitin family

BAP Subcellular locations

Mitochondrion inner membrane. Cytoplasm. Nucleus.

BAP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

BAP Sequence

DDBJ

EMBL

GenBank

BAP 3D structure

ModBase

BAP interaction

STRING

BAP Proteomic

PRIDE

BAP Genome annotation

Ensembl

GeneID

KEGG

UCSC

BAP Organism specific

CTD

MGI

BAP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BAP Gene expression

Bgee

ArrayExpress

Genevestigator

BAP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY