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Human 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (aa 1-254)

SRD5A2 Swiss Prot#

P31213

SRD5A2 Protein names

3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5-alpha-reductase 2) (5 alpha-SR2) (Type II 5-alpha reductase) (SR type 2)

SRD5A2 Gene names

SRD5A2

Organism

Human

SRD5A2 Entry name

S5A2_HUMAN

SRD5A2 Codon optimized cDNA(gene) Clone

SRD5A2 Cat #

RPE0074

Tag

SRD5A2 contains A 6x histidine tag

SRD5A2 Formulation

Liquid

SRD5A2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SRD5A2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SRD5A2 Protein

SRD5A2 Cat #

PE0074

SRD5A2 Source

recombinant

SRD5A2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SRD5A2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SRD5A2 Activity

N/A

Tag

SRD5A2 Contains A 6x histidine tag

SRD5A2 Formulation

Liquid

SRD5A2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SRD5A2 family

Steroid 5-alpha reductase family

SRD5A2 Subcellular locations

Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

SRD5A2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

SRD5A2 Sequence

DDBJ

EMBL

GenBank

SRD5A2 3D structure

ModBase

SRD5A2 interaction

STRING

SRD5A2 Proteomic

PRIDE

SRD5A2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SRD5A2 Organism specific

CTD

MGI

SRD5A2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SRD5A2 Gene expression

Bgee

ArrayExpress

Genevestigator

SRD5A2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY