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| Human Metalloproteinase inhibitor 3 (aa 24-211) |
| TIMP3 Swiss Prot# | | P35625 |
| TIMP3 Protein names | | Metalloproteinase inhibitor 3 (Tissue inhibitor of metalloproteinases 3) (TIMP-3) (Protein MIG-5) |
| TIMP3 Gene names | | TIMP3 |
| Organism | | Human |
| TIMP3 Entry name | | TIMP3_HUMAN |
| TIMP3 Codon optimized cDNA(gene) Clone |
| TIMP3 Cat # | | RPE0050 |
| Tag | | TIMP3 contains A 6x histidine tag |
| TIMP3 Formulation | | Liquid |
| TIMP3 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| TIMP3 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant TIMP3 Protein |
| TIMP3 Cat # | | PE0050 |
| TIMP3 Source | | recombinant |
| TIMP3 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| TIMP3 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| TIMP3 Activity | | N/A |
| Tag | | TIMP3 Contains A 6x histidine tag |
| TIMP3 Formulation | | Liquid |
| TIMP3 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant TIMP3 Products | | For pricing and availability Click Here >>> |
| TIMP3 family | | Protease inhibitor I35 (TIMP) family |
| TIMP3 Subcellular locations | | Secreted > extracellular space > extracellular matrix. |
| TIMP3 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. |
| TIMP3 Sequence | | DDBJ | EMBL | GenBank |
| TIMP3 3D structure | | ModBase |
| TIMP3 interaction | | STRING |
| TIMP3 Proteomic | | PRIDE |
| TIMP3 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| TIMP3 Organism specific | | CTD | MGI |
| TIMP3 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| TIMP3 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| TIMP3 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |