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Human Metalloproteinase inhibitor 3 (aa 24-211)
TIMP3 Swiss Prot#
P35625
TIMP3 Protein names
Metalloproteinase inhibitor 3 (Tissue inhibitor of metalloproteinases 3) (TIMP-3) (Protein MIG-5)
TIMP3 Gene names
TIMP3
Organism
Human
TIMP3 Entry name
TIMP3_HUMAN
TIMP3 Codon optimized cDNA(gene) Clone
TIMP3 Cat #
RPE0050
Tag
TIMP3 contains A 6x histidine tag
TIMP3 Formulation
Liquid
TIMP3 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
TIMP3 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant TIMP3 Protein
TIMP3 Cat #
PE0050
TIMP3 Source
recombinant
TIMP3 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
TIMP3 Purity
>90%, as determined by SDS-PAGE under reducing conditions
TIMP3 Activity
N/A
Tag
TIMP3 Contains A 6x histidine tag
TIMP3 Formulation
Liquid
TIMP3 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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TIMP3 family
Protease inhibitor I35 (TIMP) family
TIMP3 Subcellular locations
Secreted > extracellular space > extracellular matrix.
TIMP3 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
TIMP3 Sequence
DDBJ EMBL GenBank
TIMP3 3D structure
ModBase
TIMP3 interaction
STRING
TIMP3 Proteomic
PRIDE
TIMP3 Genome annotation
Ensembl GeneID KEGG UCSC
TIMP3 Organism specific
CTD MGI
TIMP3 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TIMP3 Gene expression
Bgee ArrayExpress Genevestigator
TIMP3 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY