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Human CD86 (aa 24 – 247)
CD28LG2 Swiss Prot#
P42081
CD28LG2 Protein names
T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86)
CD28LG2 Gene names
CD86 CD28LG2
Organism
Human
CD28LG2 Entry name
CD86_HUMAN
CD28LG2 Codon optimized cDNA(gene) Clone
CD28LG2 Cat #
RPV0852
Tag
CD28LG2 contains A 6x histidine tag
CD28LG2 Formulation
Liquid
CD28LG2 Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
CD28LG2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant CD28LG2 Protein
CD28LG2 Cat #
PV0852
CD28LG2 Source
recombinant.
CD28LG2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
CD28LG2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
CD28LG2 Activity
N/A
Tag
CD28LG2 Contains A 6x histidine tag
CD28LG2 Formulation
Liquid
CD28LG2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD28LG2 family
SUBUNIT: Homodimer. Interacts with MARCH8. Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.
CD28LG2 Subcellular locations
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
CD28LG2 FUNCTION According to UniProtKB Swiss Prot
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
CD28LG2 Sequence
DDBJ EMBL GenBank
CD28LG2 3D structure
ModBase
CD28LG2 interaction
STRING
CD28LG2 Proteomic
PRIDE
CD28LG2 Genome annotation
Ensembl GeneID KEGG UCSC
CD28LG2 Organism specific
CTD MGI
CD28LG2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD28LG2 Gene expression
Bgee ArrayExpress Genevestigator
CD28LG2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY