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| Human CD86 (aa 24 – 247) |
| CD28LG2 Swiss Prot# | | P42081 |
| CD28LG2 Protein names | | T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86) |
| CD28LG2 Gene names | | CD86 CD28LG2 |
| Organism | | Human |
| CD28LG2 Entry name | | CD86_HUMAN |
| CD28LG2 Codon optimized cDNA(gene) Clone |
| CD28LG2 Cat # | | RPV0852 |
| Tag | | CD28LG2 contains A 6x histidine tag |
| CD28LG2 Formulation | | Liquid |
| CD28LG2 Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| CD28LG2 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant CD28LG2 Protein |
| CD28LG2 Cat # | | PV0852 |
| CD28LG2 Source | | recombinant. |
| CD28LG2 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| CD28LG2 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| CD28LG2 Activity | | N/A |
| Tag | | CD28LG2 Contains A 6x histidine tag |
| CD28LG2 Formulation | | Liquid |
| CD28LG2 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD28LG2 Products | | For pricing and availability Click Here >>> |
| CD28LG2 family | | SUBUNIT: Homodimer. Interacts with MARCH8. Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses. |
| CD28LG2 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. |
| CD28LG2 FUNCTION According to UniProtKB Swiss Prot | | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
| CD28LG2 Sequence | | DDBJ | EMBL | GenBank |
| CD28LG2 3D structure | | ModBase |
| CD28LG2 interaction | | STRING |
| CD28LG2 Proteomic | | PRIDE |
| CD28LG2 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| CD28LG2 Organism specific | | CTD | MGI |
| CD28LG2 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD28LG2 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| CD28LG2 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |