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Mouse CD85k (aa 24 – 238)

Gp49b Swiss Prot#

Q64281

Gp49b Protein names

Leukocyte immunoglobulin-like receptor subfamily B member 4 (Mast cell surface glycoprotein Gp49B) (CD antigen CD85k)

Gp49b Gene names

Lilrb4 Gp49b

Organism

Mouse

Gp49b Entry name

LIRB4_MOUSE

Gp49b Codon optimized cDNA(gene) Clone

Gp49b Cat #

RPV0851

Tag

Gp49b contains A 6x histidine tag

Gp49b Formulation

Liquid

Gp49b Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Gp49b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Gp49b Protein

Gp49b Cat #

PV0851

Gp49b Source

recombinant.

Gp49b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Gp49b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Gp49b Activity

N/A

Tag

Gp49b Contains A 6x histidine tag

Gp49b Formulation

Liquid

Gp49b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Gp49b family

SUBUNIT: Binds PTPN6 when phosphorylated (By similarity).

Gp49b Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity). Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment (By similarity).

Gp49b FUNCTION According to UniProtKB Swiss Prot

Receptor for class I MHC antigens. Involved in the down-regulation of the immune response and the development of tolerance. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (By similarity).

Gp49b Sequence

DDBJ

EMBL

GenBank

Gp49b 3D structure

ModBase

Gp49b interaction

STRING

Gp49b Proteomic

PRIDE

Gp49b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Gp49b Organism specific

CTD

MGI

Gp49b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Gp49b Gene expression

Bgee

ArrayExpress

Genevestigator

Gp49b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY