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Human CD85k (aa 22 – 259)

ILT3 Swiss Prot#

Q8NHJ6

ILT3 Protein names

Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85 antigen-like family member K) (Immunoglobulin-like transcript 3) (ILT-3) (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Monocyte inhibitory receptor HM18) (CD antigen CD85k)

ILT3 Gene names

LILRB4 ILT3 LIR5

Organism

Human

ILT3 Entry name

LIRB4_HUMAN

ILT3 Codon optimized cDNA(gene) Clone

ILT3 Cat #

RPV0850

Tag

ILT3 contains A 6x histidine tag

ILT3 Formulation

Liquid

ILT3 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ILT3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ILT3 Protein

ILT3 Cat #

PV0850

ILT3 Source

recombinant.

ILT3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ILT3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ILT3 Activity

N/A

Tag

ILT3 Contains A 6x histidine tag

ILT3 Formulation

Liquid

ILT3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ILT3 family

SUBUNIT: Binds PTPN6 when phosphorylated.

ILT3 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment.

ILT3 FUNCTION According to UniProtKB Swiss Prot

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

ILT3 Sequence

DDBJ

EMBL

GenBank

ILT3 3D structure

ModBase

ILT3 interaction

STRING

ILT3 Proteomic

PRIDE

ILT3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ILT3 Organism specific

CTD

MGI

ILT3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ILT3 Gene expression

Bgee

ArrayExpress

Genevestigator

ILT3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY