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Human CD85d (aa 22 – 461)

ILT4 Swiss Prot#

Q8N423

ILT4 Protein names

Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)

ILT4 Gene names

LILRB2 ILT4 LIR2 MIR10

Organism

Human

ILT4 Entry name

LIRB2_HUMAN

ILT4 Codon optimized cDNA(gene) Clone

ILT4 Cat #

RPV0843

Tag

ILT4 contains A 6x histidine tag

ILT4 Formulation

Liquid

ILT4 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ILT4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ILT4 Protein

ILT4 Cat #

PV0843

ILT4 Source

recombinant.

ILT4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ILT4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ILT4 Activity

N/A

Tag

ILT4 Contains A 6x histidine tag

ILT4 Formulation

Liquid

ILT4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ILT4 family

SUBUNIT: Binds PTPN6 when phosphorylated. Binds FCGR1A.

ILT4 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

ILT4 FUNCTION According to UniProtKB Swiss Prot

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

ILT4 Sequence

DDBJ

EMBL

GenBank

ILT4 3D structure

ModBase

ILT4 interaction

STRING

ILT4 Proteomic

PRIDE

ILT4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ILT4 Organism specific

CTD

MGI

ILT4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ILT4 Gene expression

Bgee

ArrayExpress

Genevestigator

ILT4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY