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Human CD84 (aa 22 – 225)

SLAMF5 Swiss Prot#

Q9UIB8

SLAMF5 Protein names

SLAM family member 5 (Cell surface antigen MAX.3) (Hly9-beta) (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)

SLAMF5 Gene names

CD84 SLAMF5

Organism

Human

SLAMF5 Entry name

SLAF5_HUMAN

SLAMF5 Codon optimized cDNA(gene) Clone

SLAMF5 Cat #

RPV0838

Tag

SLAMF5 contains A 6x histidine tag

SLAMF5 Formulation

Liquid

SLAMF5 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SLAMF5 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SLAMF5 Protein

SLAMF5 Cat #

PV0838

SLAMF5 Source

recombinant.

SLAMF5 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SLAMF5 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SLAMF5 Activity

N/A

Tag

SLAMF5 Contains A 6x histidine tag

SLAMF5 Formulation

Liquid

SLAMF5 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SLAMF5 family

SUBUNIT: Homodimer; via its extracellular domain. Forms a head to tail dimer with a CD48 molecule from another cell. Interacts with SH2 domain-containing proteins SH2D1A/SAP and SH2D1B/hEAT-2. Interacts with tyrosine-protein phosphatases PTPN6 and PTPN11 via its phosphorylated cytoplasmic domain, and this interaction is blocked by SH2D1A.

SLAMF5 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.

SLAMF5 FUNCTION According to UniProtKB Swiss Prot

Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.

SLAMF5 Sequence

DDBJ

EMBL

GenBank

SLAMF5 3D structure

ModBase

SLAMF5 interaction

STRING

SLAMF5 Proteomic

PRIDE

SLAMF5 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SLAMF5 Organism specific

CTD

MGI

SLAMF5 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SLAMF5 Gene expression

Bgee

ArrayExpress

Genevestigator

SLAMF5 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY