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Human cd79b (aa 29 – 159)

B29 Swiss Prot#

P40259

B29 Protein names

B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)

B29 Gene names

CD79B B29 IGB

Organism

Human

B29 Entry name

CD79B_HUMAN

B29 Codon optimized cDNA(gene) Clone

B29 Cat #

RPV0822

Tag

B29 contains A 6x histidine tag

B29 Formulation

Liquid

B29 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

B29 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant B29 Protein

B29 Cat #

PV0822

B29 Source

recombinant.

B29 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

B29 Purity

>90%, as determined by SDS-PAGE under reducing conditions

B29 Activity

N/A

Tag

B29 Contains A 6x histidine tag

B29 Formulation

Liquid

B29 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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B29 family

SUBUNIT: Heterodimer of alpha and beta chains; disulfide-linked. Part of the B-cell antigen receptor complex where the alpha/beta chain heterodimer is non-covalently associated with an antigen-specific membrane-bound surface immunoglobulin of two heavy chains and two light chains.

B29 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts (By similarity).

B29 FUNCTION According to UniProtKB Swiss Prot

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

B29 Sequence

DDBJ

EMBL

GenBank

B29 3D structure

ModBase

B29 interaction

STRING

B29 Proteomic

PRIDE

B29 Genome annotation

Ensembl

GeneID

KEGG

UCSC

B29 Organism specific

CTD

MGI

B29 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

B29 Gene expression

Bgee

ArrayExpress

Genevestigator

B29 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY