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Rat CD42b (aa 17 – 505)

Gp1ba Swiss Prot#

D3ZQU7

Gp1ba Protein names

Platelet glycoprotein Ib alpha chain (GP-Ib alpha) (GPIb-alpha) (GPIbA) (Glycoprotein Ibalpha) (Antigen CD42b-alpha) (CD antigen CD42b) [Cleaved into: Glycocalicin]

Gp1ba Gene names

Gp1ba

Organism

Rat

Gp1ba Entry name

D3ZQU7_RAT

Gp1ba Codon optimized cDNA(gene) Clone

Gp1ba Cat #

RPV0698

Tag

Gp1ba contains A 6x histidine tag

Gp1ba Formulation

Liquid

Gp1ba Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Gp1ba Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Gp1ba Protein

Gp1ba Cat #

PV0698

Gp1ba Source

recombinant.

Gp1ba Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Gp1ba Purity

>90%, as determined by SDS-PAGE under reducing conditions

Gp1ba Activity

N/A

Tag

Gp1ba Contains A 6x histidine tag

Gp1ba Formulation

Liquid

Gp1ba Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Gp1ba family

-

Gp1ba Subcellular locations

-

Gp1ba FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Gp1ba Sequence

DDBJ

EMBL

GenBank

Gp1ba 3D structure

ModBase

Gp1ba interaction

STRING

Gp1ba Proteomic

PRIDE

Gp1ba Genome annotation

Ensembl

GeneID

KEGG

UCSC

Gp1ba Organism specific

CTD

MGI

Gp1ba Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Gp1ba Gene expression

Bgee

ArrayExpress

Genevestigator

Gp1ba Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY