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Rat cd41 (aa 32 – 420)

Itga2b Swiss Prot#

D3ZAC0

Itga2b Protein names

Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain]

Itga2b Gene names

Itga2b

Organism

Rat

Itga2b Entry name

D3ZAC0_RAT

Itga2b Codon optimized cDNA(gene) Clone

Itga2b Cat #

RPV0695

Tag

Itga2b contains A 6x histidine tag

Itga2b Formulation

Liquid

Itga2b Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Itga2b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Itga2b Protein

Itga2b Cat #

PV0695

Itga2b Source

recombinant.

Itga2b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Itga2b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Itga2b Activity

N/A

Tag

Itga2b Contains A 6x histidine tag

Itga2b Formulation

Liquid

Itga2b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Place Order for Recombinant Itga2b Products

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Itga2b family

-

Itga2b Subcellular locations

-

Itga2b FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Itga2b Sequence

DDBJ

EMBL

GenBank

Itga2b 3D structure

ModBase

Itga2b interaction

STRING

Itga2b Proteomic

PRIDE

Itga2b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Itga2b Organism specific

CTD

MGI

Itga2b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Itga2b Gene expression

Bgee

ArrayExpress

Genevestigator

Itga2b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY