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| Mouse CD357 (aa 20 – 153) |
| Gitr Swiss Prot# | | O35714 |
| Gitr Protein names | | Tumor necrosis factor receptor superfamily member 18 (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357) |
| Gitr Gene names | | Tnfrsf18 Gitr |
| Organism | | Mouse |
| Gitr Entry name | | TNR18_MOUSE |
| Gitr Codon optimized cDNA(gene) Clone |
| Gitr Cat # | | RPV0648 |
| Tag | | Gitr contains A 6x histidine tag |
| Gitr Formulation | | Liquid |
| Gitr Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Gitr Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Gitr Protein |
| Gitr Cat # | | PV0648 |
| Gitr Source | | recombinant. |
| Gitr Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Gitr Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Gitr Activity | | N/A |
| Tag | | Gitr Contains A 6x histidine tag |
| Gitr Formulation | | Liquid |
| Gitr Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Gitr Products | | For pricing and availability Click Here >>> |
| Gitr family | | SUBUNIT: Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 (By similarity). Binds through its C-terminus to SIVA1/SIVA. |
| Gitr Subcellular locations | | SUBCELLULAR LOCATION: Isoform A: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform B: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform C: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform D: Secreted. |
| Gitr FUNCTION According to UniProtKB Swiss Prot | | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity). |
| Gitr Sequence | | DDBJ | EMBL | GenBank |
| Gitr 3D structure | | ModBase |
| Gitr interaction | | STRING |
| Gitr Proteomic | | PRIDE |
| Gitr Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Gitr Organism specific | | CTD | MGI |
| Gitr Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Gitr Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Gitr Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |