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Human CD357 (aa 26 – 162)

AITR Swiss Prot#

Q9Y5U5

AITR Protein names

Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357)

AITR Gene names

TNFRSF18 AITR GITR UNQ319/PRO364

Organism

Human

AITR Entry name

TNR18_HUMAN

AITR Codon optimized cDNA(gene) Clone

AITR Cat #

RPV0647

Tag

AITR contains A 6x histidine tag

AITR Formulation

Liquid

AITR Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

AITR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant AITR Protein

AITR Cat #

PV0647

AITR Source

recombinant.

AITR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

AITR Purity

>90%, as determined by SDS-PAGE under reducing conditions

AITR Activity

N/A

Tag

AITR Contains A 6x histidine tag

AITR Formulation

Liquid

AITR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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AITR family

SUBUNIT: Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6. Binds through its C-terminus to SIVA1/SIVA.

AITR Subcellular locations

SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Secreted.

AITR FUNCTION According to UniProtKB Swiss Prot

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

AITR Sequence

DDBJ

EMBL

GenBank

AITR 3D structure

ModBase

AITR interaction

STRING

AITR Proteomic

PRIDE

AITR Genome annotation

Ensembl

GeneID

KEGG

UCSC

AITR Organism specific

CTD

MGI

AITR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

AITR Gene expression

Bgee

ArrayExpress

Genevestigator

AITR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY