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Human cd338 (aa 557 – 630)

ABCP Swiss Prot#

Q9UNQ0

ABCP Protein names

ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (CD antigen CD338)

ABCP Gene names

ABCG2 ABCP BCRP BCRP1 MXR

Organism

Human

ABCP Entry name

ABCG2_HUMAN

ABCP Codon optimized cDNA(gene) Clone

ABCP Cat #

RPV0622

Tag

ABCP contains A 6x histidine tag

ABCP Formulation

Liquid

ABCP Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ABCP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ABCP Protein

ABCP Cat #

PV0622

ABCP Source

recombinant.

ABCP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ABCP Purity

>90%, as determined by SDS-PAGE under reducing conditions

ABCP Activity

N/A

Tag

ABCP Contains A 6x histidine tag

ABCP Formulation

Liquid

ABCP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ABCP family

SUBUNIT: Monomer or homodimer; disulfide-linked.

ABCP Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

ABCP FUNCTION According to UniProtKB Swiss Prot

Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

ABCP Sequence

DDBJ

EMBL

GenBank

ABCP 3D structure

ModBase

ABCP interaction

STRING

ABCP Proteomic

PRIDE

ABCP Genome annotation

Ensembl

GeneID

KEGG

UCSC

ABCP Organism specific

CTD

MGI

ABCP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ABCP Gene expression

Bgee

ArrayExpress

Genevestigator

ABCP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY