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Mouse cd331 (aa 22 – 376)

Flg Swiss Prot#

P16092

Flg Protein names

Basic fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331)

Flg Gene names

Fgfr1 Flg

Organism

Mouse

Flg Entry name

FGFR1_MOUSE

Flg Codon optimized cDNA(gene) Clone

Flg Cat #

RPV0606

Tag

Flg contains A 6x histidine tag

Flg Formulation

Liquid

Flg Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Flg Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Flg Protein

Flg Cat #

PV0606

Flg Source

recombinant.

Flg Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Flg Purity

>90%, as determined by SDS-PAGE under reducing conditions

Flg Activity

N/A

Tag

Flg Contains A 6x histidine tag

Flg Formulation

Liquid

Flg Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Flg family

SUBUNIT: Homodimer. Interacts with KLB, KL and FGF23. Interacts with SHB and GRB10. Interacts with PLCG1 (via SH2 domains). Interacts with KAL1; this interaction does not interfere with FGF2-binding to FGFR1, but prevents binding of heparin-bound FGF2 (By similarity).

Flg Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Flg FUNCTION According to UniProtKB Swiss Prot

Receptor for fibroblast growth factors FGF2 and FGF1. Receptor for FGF23 in the presence of KL (By similarity). Promotes mitogenesis in response to fibroblast growth factors. Activates PLCG1 (By similarity).

Flg Sequence

DDBJ

EMBL

GenBank

Flg 3D structure

ModBase

Flg interaction

STRING

Flg Proteomic

PRIDE

Flg Genome annotation

Ensembl

GeneID

KEGG

UCSC

Flg Organism specific

CTD

MGI

Flg Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Flg Gene expression

Bgee

ArrayExpress

Genevestigator

Flg Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY