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| Human cd331 (aa 22 – 376) |
| FGFBR Swiss Prot# | | P11362 |
| FGFBR Protein names | | Basic fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 2) (FLT-2) (Proto-oncogene c-Fgr) (CD antigen CD331) |
| FGFBR Gene names | | FGFR1 FGFBR FLG FLT2 |
| Organism | | Human |
| FGFBR Entry name | | FGFR1_HUMAN |
| FGFBR Codon optimized cDNA(gene) Clone |
| FGFBR Cat # | | RPV0605 |
| Tag | | FGFBR contains A 6x histidine tag |
| FGFBR Formulation | | Liquid |
| FGFBR Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| FGFBR Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant FGFBR Protein |
| FGFBR Cat # | | PV0605 |
| FGFBR Source | | recombinant. |
| FGFBR Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| FGFBR Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| FGFBR Activity | | N/A |
| Tag | | FGFBR Contains A 6x histidine tag |
| FGFBR Formulation | | Liquid |
| FGFBR Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant FGFBR Products | | For pricing and availability Click Here >>> |
| FGFBR family | | SUBUNIT: Homodimer. Interacts with KLB (By similarity). Interacts with KL and FGF23 (By similarity). Interacts with SHB and GRB10. Interacts with PLCG1 (via SH2 domains). Interacts with KAL1; this interaction does not interfere with FGF2-binding to FGFR1, but prevents binding of heparin-bound FGF2. |
| FGFBR Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| FGFBR FUNCTION According to UniProtKB Swiss Prot | | Receptor for fibroblast growth factors FGF2 and FGF1. Receptor for FGF23 in the presence of KL (By similarity). Promotes mitogenesis in response to fibroblast growth factors. Activates PLCG1. |
| FGFBR Sequence | | DDBJ | EMBL | GenBank |
| FGFBR 3D structure | | ModBase |
| FGFBR interaction | | STRING |
| FGFBR Proteomic | | PRIDE |
| FGFBR Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| FGFBR Organism specific | | CTD | MGI |
| FGFBR Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| FGFBR Gene expression | | Bgee | ArrayExpress | Genevestigator |
| FGFBR Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |