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Human cd326 (aa 24 – 265)

GA733-2 Swiss Prot#

P16422

GA733-2 Protein names

Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)

GA733-2 Gene names

EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1

Organism

Human

GA733-2 Entry name

EPCAM_HUMAN

GA733-2 Codon optimized cDNA(gene) Clone

GA733-2 Cat #

RPV0597

Tag

GA733-2 contains A 6x histidine tag

GA733-2 Formulation

Liquid

GA733-2 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

GA733-2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant GA733-2 Protein

GA733-2 Cat #

PV0597

GA733-2 Source

recombinant.

GA733-2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

GA733-2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

GA733-2 Activity

N/A

Tag

GA733-2 Contains A 6x histidine tag

GA733-2 Formulation

Liquid

GA733-2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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GA733-2 family

SUBUNIT: Monomer. Interacts with phosphorylated CLDN7.

GA733-2 Subcellular locations

SUBCELLULAR LOCATION: Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Co-localizes with CLDN7 at the lateral cell membrane and tight junction.

GA733-2 FUNCTION According to UniProtKB Swiss Prot

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

GA733-2 Sequence

DDBJ

EMBL

GenBank

GA733-2 3D structure

ModBase

GA733-2 interaction

STRING

GA733-2 Proteomic

PRIDE

GA733-2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

GA733-2 Organism specific

CTD

MGI

GA733-2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

GA733-2 Gene expression

Bgee

ArrayExpress

Genevestigator

GA733-2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY