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Human cd325 (aa 160 – 724)

CDHN Swiss Prot#

P19022

CDHN Protein names

Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)

CDHN Gene names

CDH2 CDHN NCAD

Organism

Human

CDHN Entry name

CADH2_HUMAN

CDHN Codon optimized cDNA(gene) Clone

CDHN Cat #

RPV0594

Tag

CDHN contains A 6x histidine tag

CDHN Formulation

Liquid

CDHN Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CDHN Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CDHN Protein

CDHN Cat #

PV0594

CDHN Source

recombinant.

CDHN Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CDHN Purity

>90%, as determined by SDS-PAGE under reducing conditions

CDHN Activity

N/A

Tag

CDHN Contains A 6x histidine tag

CDHN Formulation

Liquid

CDHN Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CDHN family

SUBUNIT: Interacts with CDCP1. Interacts with PCDH8; this complex may also include TAOK2. The interaction with PCDH8 may lead to internalization through TAOK2/p38 MAPK pathway (By similarity).

CDHN Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.

CDHN FUNCTION According to UniProtKB Swiss Prot

Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

CDHN Sequence

DDBJ

EMBL

GenBank

CDHN 3D structure

ModBase

CDHN interaction

STRING

CDHN Proteomic

PRIDE

CDHN Genome annotation

Ensembl

GeneID

KEGG

UCSC

CDHN Organism specific

CTD

MGI

CDHN Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CDHN Gene expression

Bgee

ArrayExpress

Genevestigator

CDHN Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY