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Rat cd321 (aa 27 – 238)
Jam1 Swiss Prot#
Q9JHY1
Jam1 Protein names
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321)
Jam1 Gene names
F11r Jam1
Organism
Rat
Jam1 Entry name
JAM1_RAT
Jam1 Codon optimized cDNA(gene) Clone
Jam1 Cat #
RPV0587
Tag
Jam1 contains A 6x histidine tag
Jam1 Formulation
Liquid
Jam1 Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Jam1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Jam1 Protein
Jam1 Cat #
PV0587
Jam1 Source
recombinant.
Jam1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Jam1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Jam1 Activity
N/A
Tag
Jam1 Contains A 6x histidine tag
Jam1 Formulation
Liquid
Jam1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Jam1 family
SUBUNIT: Interacts with the ninth PDZ domain of MPDZ. Interacts with the first PDZ domain of PARD3. The association between PARD3 and PARD6B probably disrupts this interaction. Interacts with the orthoreovirus sigma-1 capsid protein (By similarity).
Jam1 Subcellular locations
SUBCELLULAR LOCATION: Cell junction, tight junction (By similarity). Cell membrane; Single-pass type I membrane protein (By similarity). Note=Localized at tight junctions of both epithelial and endothelial cells (By similarity).
Jam1 FUNCTION According to UniProtKB Swiss Prot
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus (By similarity).
Jam1 Sequence
DDBJ EMBL GenBank
Jam1 3D structure
ModBase
Jam1 interaction
STRING
Jam1 Proteomic
PRIDE
Jam1 Genome annotation
Ensembl GeneID KEGG UCSC
Jam1 Organism specific
CTD MGI
Jam1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Jam1 Gene expression
Bgee ArrayExpress Genevestigator
Jam1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY