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Mouse CD32 (aa 30 – 210)

Fcgr2b Swiss Prot#

P08101

Fcgr2b Protein names

Low affinity immunoglobulin gamma Fc region receptor II (Fc gamma receptor IIB) (Fc-gamma RII) (Fc-gamma-RIIB) (FcRII) (IgG Fc receptor II beta) (Lymphocyte antigen 17) (Ly-17) (CD antigen CD32)

Fcgr2b Gene names

Fcgr2 Fcgr2b Ly-17

Organism

Mouse

Fcgr2b Entry name

FCGR2_MOUSE

Fcgr2b Codon optimized cDNA(gene) Clone

Fcgr2b Cat #

RPV0580

Tag

Fcgr2b contains A 6x histidine tag

Fcgr2b Formulation

Liquid

Fcgr2b Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Fcgr2b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fcgr2b Protein

Fcgr2b Cat #

PV0580

Fcgr2b Source

recombinant.

Fcgr2b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Fcgr2b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Fcgr2b Activity

N/A

Tag

Fcgr2b Contains A 6x histidine tag

Fcgr2b Formulation

Liquid

Fcgr2b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Fcgr2b family

-

Fcgr2b Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform IIB1: Cytoplasm, cytoskeleton. Note=Binds the cytoskeleton and is not localized in endocytotic pits.; SUBCELLULAR LOCATION: Isoform IIB3: Secreted. Note=Released as a soluble molecule.

Fcgr2b FUNCTION According to UniProtKB Swiss Prot

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.

Fcgr2b Sequence

DDBJ

EMBL

GenBank

Fcgr2b 3D structure

ModBase

Fcgr2b interaction

STRING

Fcgr2b Proteomic

PRIDE

Fcgr2b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Fcgr2b Organism specific

CTD

MGI

Fcgr2b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Fcgr2b Gene expression

Bgee

ArrayExpress

Genevestigator

Fcgr2b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY