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Human CD32 (aa 43 – 217)

CD32 Swiss Prot#

P31994

CD32 Protein names

Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)

CD32 Gene names

FCGR2B CD32 FCG2 IGFR2

Organism

Human

CD32 Entry name

FCG2B_HUMAN

CD32 Codon optimized cDNA(gene) Clone

CD32 Cat #

RPV0579

Tag

CD32 contains A 6x histidine tag

CD32 Formulation

Liquid

CD32 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CD32 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CD32 Protein

CD32 Cat #

PV0579

CD32 Source

recombinant.

CD32 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CD32 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CD32 Activity

N/A

Tag

CD32 Contains A 6x histidine tag

CD32 Formulation

Liquid

CD32 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CD32 family

SUBUNIT: Isoform IIB1 interacts with measles virus N protein. N protein is released in the blood following lysis of measles infected cells. This interaction presumably block inflammatory immune response. Interacts with INPP5D/SHIP1.

CD32 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.

CD32 FUNCTION According to UniProtKB Swiss Prot

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

CD32 Sequence

DDBJ

EMBL

GenBank

CD32 3D structure

ModBase

CD32 interaction

STRING

CD32 Proteomic

PRIDE

CD32 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CD32 Organism specific

CTD

MGI

CD32 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD32 Gene expression

Bgee

ArrayExpress

Genevestigator

CD32 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY