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Mouse cd316 (aa 26 – 577)
Ewi2 Swiss Prot#
Q8R366
Ewi2 Protein names
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocyte-associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory-like protein) (CD antigen CD316)
Ewi2 Gene names
Igsf8 Ewi2 Kct4 Pgrl
Organism
Mouse
Ewi2 Entry name
IGSF8_MOUSE
Ewi2 Codon optimized cDNA(gene) Clone
Ewi2 Cat #
RPV0568
Tag
Ewi2 contains A 6x histidine tag
Ewi2 Formulation
Liquid
Ewi2 Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Ewi2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Ewi2 Protein
Ewi2 Cat #
PV0568
Ewi2 Source
recombinant.
Ewi2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Ewi2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Ewi2 Activity
N/A
Tag
Ewi2 Contains A 6x histidine tag
Ewi2 Formulation
Liquid
Ewi2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Ewi2 family
SUBUNIT: Interacts directly with CD82 and CD9/tetraspanin-29. Also interacts with integrin alpha-3/beta-1 and integrin alpha-4/beta-1 (By similarity). Interacts with CD81/tetraspanin-28.
Ewi2 Subcellular locations
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
Ewi2 FUNCTION According to UniProtKB Swiss Prot
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Ewi2 Sequence
DDBJ EMBL GenBank
Ewi2 3D structure
ModBase
Ewi2 interaction
STRING
Ewi2 Proteomic
PRIDE
Ewi2 Genome annotation
Ensembl GeneID KEGG UCSC
Ewi2 Organism specific
CTD MGI
Ewi2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Ewi2 Gene expression
Bgee ArrayExpress Genevestigator
Ewi2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY