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| Mouse cd316 (aa 26 – 577) |
| Ewi2 Swiss Prot# | | Q8R366 |
| Ewi2 Protein names | | Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocyte-associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory-like protein) (CD antigen CD316) |
| Ewi2 Gene names | | Igsf8 Ewi2 Kct4 Pgrl |
| Organism | | Mouse |
| Ewi2 Entry name | | IGSF8_MOUSE |
| Ewi2 Codon optimized cDNA(gene) Clone |
| Ewi2 Cat # | | RPV0568 |
| Tag | | Ewi2 contains A 6x histidine tag |
| Ewi2 Formulation | | Liquid |
| Ewi2 Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Ewi2 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Ewi2 Protein |
| Ewi2 Cat # | | PV0568 |
| Ewi2 Source | | recombinant. |
| Ewi2 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Ewi2 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Ewi2 Activity | | N/A |
| Tag | | Ewi2 Contains A 6x histidine tag |
| Ewi2 Formulation | | Liquid |
| Ewi2 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Ewi2 Products | | For pricing and availability Click Here >>> |
| Ewi2 family | | SUBUNIT: Interacts directly with CD82 and CD9/tetraspanin-29. Also interacts with integrin alpha-3/beta-1 and integrin alpha-4/beta-1 (By similarity). Interacts with CD81/tetraspanin-28. |
| Ewi2 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential). |
| Ewi2 FUNCTION According to UniProtKB Swiss Prot | | May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. |
| Ewi2 Sequence | | DDBJ | EMBL | GenBank |
| Ewi2 3D structure | | ModBase |
| Ewi2 interaction | | STRING |
| Ewi2 Proteomic | | PRIDE |
| Ewi2 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Ewi2 Organism specific | | CTD | MGI |
| Ewi2 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Ewi2 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Ewi2 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |