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Human cd309 (aa 421 – 548)

FLK1 Swiss Prot#

P35968

FLK1 Protein names

Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)

FLK1 Gene names

KDR FLK1

Organism

Human

FLK1 Entry name

VGFR2_HUMAN

FLK1 Codon optimized cDNA(gene) Clone

FLK1 Cat #

RPV0554

Tag

FLK1 contains A 6x histidine tag

FLK1 Formulation

Liquid

FLK1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FLK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FLK1 Protein

FLK1 Cat #

PV0554

FLK1 Source

recombinant.

FLK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FLK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

FLK1 Activity

N/A

Tag

FLK1 Contains A 6x histidine tag

FLK1 Formulation

Liquid

FLK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FLK1 family

SUBUNIT: Interacts with MYOF (By similarity). Interacts with SHB; upon VEGF activation. Interacts with HIV-1 Tat.

FLK1 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

FLK1 FUNCTION According to UniProtKB Swiss Prot

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

FLK1 Sequence

DDBJ

EMBL

GenBank

FLK1 3D structure

ModBase

FLK1 interaction

STRING

FLK1 Proteomic

PRIDE

FLK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

FLK1 Organism specific

CTD

MGI

FLK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FLK1 Gene expression

Bgee

ArrayExpress

Genevestigator

FLK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY