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Mouse cd304 (aa 431 – 583)

Nrp Swiss Prot#

P97333

Nrp Protein names

Neuropilin-1 (A5 protein) (CD antigen CD304)

Nrp Gene names

Nrp1 Nrp

Organism

Mouse

Nrp Entry name

NRP1_MOUSE

Nrp Codon optimized cDNA(gene) Clone

Nrp Cat #

RPV0547

Tag

Nrp contains A 6x histidine tag

Nrp Formulation

Liquid

Nrp Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nrp Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nrp Protein

Nrp Cat #

PV0547

Nrp Source

recombinant.

Nrp Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nrp Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nrp Activity

N/A

Tag

Nrp Contains A 6x histidine tag

Nrp Formulation

Liquid

Nrp Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nrp family

SUBUNIT: Homodimer, and heterodimer with NRP2. Binds PLXNB1 (By similarity).

Nrp Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Nrp FUNCTION According to UniProtKB Swiss Prot

Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis (By similarity).

Nrp Sequence

DDBJ

EMBL

GenBank

Nrp 3D structure

ModBase

Nrp interaction

STRING

Nrp Proteomic

PRIDE

Nrp Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nrp Organism specific

CTD

MGI

Nrp Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nrp Gene expression

Bgee

ArrayExpress

Genevestigator

Nrp Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY