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Human cd299 (aa 71 – 399)

CD209L Swiss Prot#

Q9H2X3

CD209L Protein names

C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299)

CD209L Gene names

CLEC4M CD209L CD209L1 CD299

Organism

Human

CD209L Entry name

CLC4M_HUMAN

CD209L Codon optimized cDNA(gene) Clone

CD209L Cat #

RPV0515

Tag

CD209L contains A 6x histidine tag

CD209L Formulation

Liquid

CD209L Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CD209L Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CD209L Protein

CD209L Cat #

PV0515

CD209L Source

recombinant.

CD209L Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CD209L Purity

>90%, as determined by SDS-PAGE under reducing conditions

CD209L Activity

N/A

Tag

CD209L Contains A 6x histidine tag

CD209L Formulation

Liquid

CD209L Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CD209L family

SUBUNIT: Homotetramer. Binds to many viral surface glycoproteins such as HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus S protein.

CD209L Subcellular locations

SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 2: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 3: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 5: Secreted (Potential). ; SUBCELLULAR LOCATION: Isoform 6: Secreted (Potential). ; SUBCELLULAR LOCATION: Isoform 7: Secreted (Potential). ; SUBCELLULAR LOCATION: Isoform 10: Secreted (Potential).

CD209L FUNCTION According to UniProtKB Swiss Prot

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.

CD209L Sequence

DDBJ

EMBL

GenBank

CD209L 3D structure

ModBase

CD209L interaction

STRING

CD209L Proteomic

PRIDE

CD209L Genome annotation

Ensembl

GeneID

KEGG

UCSC

CD209L Organism specific

CTD

MGI

CD209L Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD209L Gene expression

Bgee

ArrayExpress

Genevestigator

CD209L Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY