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Mouse CD288 (aa 24 – 424)

Tlr8 Swiss Prot#

P58682

Tlr8 Protein names

Toll-like receptor 8 (CD antigen CD288)

Tlr8 Gene names

Tlr8

Organism

Mouse

Tlr8 Entry name

TLR8_MOUSE

Tlr8 Codon optimized cDNA(gene) Clone

Tlr8 Cat #

RPV0490

Tag

Tlr8 contains A 6x histidine tag

Tlr8 Formulation

Liquid

Tlr8 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tlr8 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tlr8 Protein

Tlr8 Cat #

PV0490

Tlr8 Source

recombinant.

Tlr8 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tlr8 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tlr8 Activity

N/A

Tag

Tlr8 Contains A 6x histidine tag

Tlr8 Formulation

Liquid

Tlr8 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tlr8 family

SUBUNIT: Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with UNC93B1.

Tlr8 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (By similarity).

Tlr8 FUNCTION According to UniProtKB Swiss Prot

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B. activation, cytokine secretion and the inflammatory response (By similarity).

Tlr8 Sequence

DDBJ

EMBL

GenBank

Tlr8 3D structure

ModBase

Tlr8 interaction

STRING

Tlr8 Proteomic

PRIDE

Tlr8 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tlr8 Organism specific

CTD

MGI

Tlr8 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tlr8 Gene expression

Bgee

ArrayExpress

Genevestigator

Tlr8 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY