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Human CD288 (aa 27 – 427)

UNQ249/PRO286 Swiss Prot#

Q9NR97

UNQ249/PRO286 Protein names

Toll-like receptor 8 (CD antigen CD288)

UNQ249/PRO286 Gene names

TLR8 UNQ249/PRO286

Organism

Human

UNQ249/PRO286 Entry name

TLR8_HUMAN

UNQ249/PRO286 Codon optimized cDNA(gene) Clone

UNQ249/PRO286 Cat #

RPV0489

Tag

UNQ249/PRO286 contains A 6x histidine tag

UNQ249/PRO286 Formulation

Liquid

UNQ249/PRO286 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

UNQ249/PRO286 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant UNQ249/PRO286 Protein

UNQ249/PRO286 Cat #

PV0489

UNQ249/PRO286 Source

recombinant.

UNQ249/PRO286 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

UNQ249/PRO286 Purity

>90%, as determined by SDS-PAGE under reducing conditions

UNQ249/PRO286 Activity

N/A

Tag

UNQ249/PRO286 Contains A 6x histidine tag

UNQ249/PRO286 Formulation

Liquid

UNQ249/PRO286 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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UNQ249/PRO286 family

SUBUNIT: Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1 (By similarity).

UNQ249/PRO286 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (By similarity).

UNQ249/PRO286 FUNCTION According to UniProtKB Swiss Prot

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

UNQ249/PRO286 Sequence

DDBJ

EMBL

GenBank

UNQ249/PRO286 3D structure

ModBase

UNQ249/PRO286 interaction

STRING

UNQ249/PRO286 Proteomic

PRIDE

UNQ249/PRO286 Genome annotation

Ensembl

GeneID

KEGG

UCSC

UNQ249/PRO286 Organism specific

CTD

MGI

UNQ249/PRO286 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

UNQ249/PRO286 Gene expression

Bgee

ArrayExpress

Genevestigator

UNQ249/PRO286 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY