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Human CD286 (aa 32 – 586)

TLR6 Swiss Prot#

Q9Y2C9

TLR6 Protein names

Toll-like receptor 6 (CD antigen CD286)

TLR6 Gene names

TLR6

Organism

Human

TLR6 Entry name

TLR6_HUMAN

TLR6 Codon optimized cDNA(gene) Clone

TLR6 Cat #

RPV0486

Tag

TLR6 contains A 6x histidine tag

TLR6 Formulation

Liquid

TLR6 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TLR6 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TLR6 Protein

TLR6 Cat #

PV0486

TLR6 Source

recombinant.

TLR6 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TLR6 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TLR6 Activity

N/A

Tag

TLR6 Contains A 6x histidine tag

TLR6 Formulation

Liquid

TLR6 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TLR6 family

SUBUNIT: Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains (By similarity).

TLR6 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein (By similarity).

TLR6 FUNCTION According to UniProtKB Swiss Prot

Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.

TLR6 Sequence

DDBJ

EMBL

GenBank

TLR6 3D structure

ModBase

TLR6 interaction

STRING

TLR6 Proteomic

PRIDE

TLR6 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TLR6 Organism specific

CTD

MGI

TLR6 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TLR6 Gene expression

Bgee

ArrayExpress

Genevestigator

TLR6 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY