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Mouse CD284 (aa 26 – 426)

Lps Swiss Prot#

Q9QUK6

Lps Protein names

Toll-like receptor 4 (CD antigen CD284)

Lps Gene names

Tlr4 Lps

Organism

Mouse

Lps Entry name

TLR4_MOUSE

Lps Codon optimized cDNA(gene) Clone

Lps Cat #

RPV0484

Tag

Lps contains A 6x histidine tag

Lps Formulation

Liquid

Lps Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Lps Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Lps Protein

Lps Cat #

PV0484

Lps Source

recombinant.

Lps Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Lps Purity

>90%, as determined by SDS-PAGE under reducing conditions

Lps Activity

N/A

Tag

Lps Contains A 6x histidine tag

Lps Formulation

Liquid

Lps Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Lps family

SUBUNIT: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Binding to bacterial LPS leads to homodimerization. Interacts with LY96 via the extracellular domain. Interacts with MYD88 and TIRAP via their respective TIR domains. Interacts with NOX4 (By similarity). Interacts with CNPY3.

Lps Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (By similarity).

Lps FUNCTION According to UniProtKB Swiss Prot

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Lps Sequence

DDBJ

EMBL

GenBank

Lps 3D structure

ModBase

Lps interaction

STRING

Lps Proteomic

PRIDE

Lps Genome annotation

Ensembl

GeneID

KEGG

UCSC

Lps Organism specific

CTD

MGI

Lps Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Lps Gene expression

Bgee

ArrayExpress

Genevestigator

Lps Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY