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Human CD274 (aa 19 – 238)

B7H1 Swiss Prot#

Q9NZQ7

B7H1 Protein names

Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274)

B7H1 Gene names

CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1

Organism

Human

B7H1 Entry name

PD1L1_HUMAN

B7H1 Codon optimized cDNA(gene) Clone

B7H1 Cat #

RPV0455

Tag

B7H1 contains A 6x histidine tag

B7H1 Formulation

Liquid

B7H1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

B7H1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant B7H1 Protein

B7H1 Cat #

PV0455

B7H1 Source

recombinant.

B7H1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

B7H1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

B7H1 Activity

N/A

Tag

B7H1 Contains A 6x histidine tag

B7H1 Formulation

Liquid

B7H1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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B7H1 family

SUBUNIT: Interacts with PDCD1.

B7H1 Subcellular locations

SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Endomembrane system; Single-pass type I membrane protein.

B7H1 FUNCTION According to UniProtKB Swiss Prot

Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

B7H1 Sequence

DDBJ

EMBL

GenBank

B7H1 3D structure

ModBase

B7H1 interaction

STRING

B7H1 Proteomic

PRIDE

B7H1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

B7H1 Organism specific

CTD

MGI

B7H1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

B7H1 Gene expression

Bgee

ArrayExpress

Genevestigator

B7H1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY