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Rat cd227 (aa 241-535)

Muc-1 Swiss Prot#

B2GV31

Muc-1 Protein names

Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Carcinoma-associated mucin) (Episialin) (H23AG) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]

Muc-1 Gene names

Muc1 Muc-1

Organism

Rat

Muc-1 Entry name

B2GV31_RAT

Muc-1 Codon optimized cDNA(gene) Clone

Muc-1 Cat #

RPV0374

Tag

Muc-1 contains A 6x histidine tag

Muc-1 Formulation

Liquid

Muc-1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Muc-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Muc-1 Protein

Muc-1 Cat #

PV0374

Muc-1 Source

recombinant.

Muc-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Muc-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Muc-1 Activity

N/A

Tag

Muc-1 Contains A 6x histidine tag

Muc-1 Formulation

Liquid

Muc-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Muc-1 family

-

Muc-1 Subcellular locations

-

Muc-1 FUNCTION According to UniProtKB Swiss Prot

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.; The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, Src and NF-kappaB pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Regulates P53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of P53 and represses P53 activity.

Muc-1 Sequence

DDBJ

EMBL

GenBank

Muc-1 3D structure

ModBase

Muc-1 interaction

STRING

Muc-1 Proteomic

PRIDE

Muc-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Muc-1 Organism specific

CTD

MGI

Muc-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Muc-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Muc-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY