All rights reserved

Bio-Magnetic Purification ......   A Powerful Tool for Life Science Research Affinity Magnetic Beads >>> Amine >>                 Aldehyde >>                  Carboxy >>    CDI >>                      DVS >>                          DADPA  >>     Epoxy  >>                 Hydrazide >>                 Hyrdoxy >>     Iodoacetyl >>           NHS >>                         Sulghydry >> Tosyl >>                   Thiol >>                         Silica >> EDTA >>                   IDA >>                      Streptavidin  >> Monomer Avidin >>          Reversed-Phase Magnetic Beads >>> C4 >>                          C8 >>                       C18 >>   Cyanopropyl >>          Phenyl >>                 Dipheny >> Ion Exchange Magnetic Beads >>> DEAE >>                   PSA >>                  SAX >> WCX >>                    SCX >>           Hydroxyapatite  >> Antibody Purification & IP >>> Protein A >>           Protein G >>        Protein A/G >> Protein L >> Recombinant Protein Purification >>> Ni+ Charged Beads >>    Co + Charged Beads >> GST >> DNA & RNA Purification >>> Plant/Animal >>         Bacteria >>             Blood >> Saliva >>                   Stool >>                  Food >> mRNA >>                    PCR >>                   Soil >> Endotoxin Removal Magnetic Beads >>>   Abundant Protein Removal >>> HSA  Removal >>                                    IgG  Removal >> Cell Isolation >>> Bacteria >>                                              Viurs >> More Application >>

Home BioMagnetic Beads Recombinant Protein & Codon Optimized cDNA Service Order Contact Us New Products

For cDNA or Recombinant Protein Search ( Input   Gene name, or Protein Name, or Swiss -prot Accession Number Bioclone Distributor >>>

Email: info@bioclone.us ;  order@bioclone.us

More Than 20,000   Recombinant Protein & cDNA(gene) Virus Antigen  >>> Bacterial Antigen >>> Parasite Antigen  >>> Cell Surface CD Marker >> Cytokines >>> Kinase  >>> Transduction >>> Transcription Factor >>> Common Disease-related Proteins >>> Phosphatase >>> Cancer >>> Drug  metabolism >>> Neuroscience >>> G protein coupled receptors   >>> Stem cell >> Kinase >>> Disease >.>> Toxin & Allergen >>> Cytoskeleton >>

Human cd22 (aa 20 – 420)

SIGLEC2 Swiss Prot#

P20273

SIGLEC2 Protein names

B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)

SIGLEC2 Gene names

CD22 SIGLEC2

Organism

Human

SIGLEC2 Entry name

CD22_HUMAN

SIGLEC2 Codon optimized cDNA(gene) Clone

SIGLEC2 Cat #

RPV0360

Tag

SIGLEC2 contains A 6x histidine tag

SIGLEC2 Formulation

Liquid

SIGLEC2 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SIGLEC2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SIGLEC2 Protein

SIGLEC2 Cat #

PV0360

SIGLEC2 Source

recombinant.

SIGLEC2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SIGLEC2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SIGLEC2 Activity

N/A

Tag

SIGLEC2 Contains A 6x histidine tag

SIGLEC2 Formulation

Liquid

SIGLEC2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Place Order for Recombinant SIGLEC2 Products

For pricing and availability Click Here >>>

SIGLEC2 family

SUBUNIT: Predominantly monomer of isoform CD22-beta. Also found as heterodimer of isoform CD22-beta and a shorter isoform. Interacts with PTPN6/SHP-1, LYN, SYK, PIK3R1/PIK3R2 and PLCG1 upon phosphorylation. Interacts with GRB2, INPP5D and SHC1 upon phosphorylation (By similarity). May form a complex with INPP5D/SHIP, GRB2 and SHC1.

SIGLEC2 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.

SIGLEC2 FUNCTION According to UniProtKB Swiss Prot

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

SIGLEC2 Sequence

DDBJ

EMBL

GenBank

SIGLEC2 3D structure

ModBase

SIGLEC2 interaction

STRING

SIGLEC2 Proteomic

PRIDE

SIGLEC2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SIGLEC2 Organism specific

CTD

MGI

SIGLEC2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SIGLEC2 Gene expression

Bgee

ArrayExpress

Genevestigator

SIGLEC2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY