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Human cd207 (aa 65 – 328)

CLEC4K Swiss Prot#

Q9UJ71

CLEC4K Protein names

C-type lectin domain family 4 member K (Langerin) (CD antigen CD207)

CLEC4K Gene names

CD207 CLEC4K

Organism

Human

CLEC4K Entry name

CLC4K_HUMAN

CLEC4K Codon optimized cDNA(gene) Clone

CLEC4K Cat #

RPV0336

Tag

CLEC4K contains A 6x histidine tag

CLEC4K Formulation

Liquid

CLEC4K Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CLEC4K Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CLEC4K Protein

CLEC4K Cat #

PV0336

CLEC4K Source

recombinant.

CLEC4K Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CLEC4K Purity

>90%, as determined by SDS-PAGE under reducing conditions

CLEC4K Activity

N/A

Tag

CLEC4K Contains A 6x histidine tag

CLEC4K Formulation

Liquid

CLEC4K Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CLEC4K family

SUBUNIT: Homotrimer.

CLEC4K Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. Note=Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.

CLEC4K FUNCTION According to UniProtKB Swiss Prot

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

CLEC4K Sequence

DDBJ

EMBL

GenBank

CLEC4K 3D structure

ModBase

CLEC4K interaction

STRING

CLEC4K Proteomic

PRIDE

CLEC4K Genome annotation

Ensembl

GeneID

KEGG

UCSC

CLEC4K Organism specific

CTD

MGI

CLEC4K Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CLEC4K Gene expression

Bgee

ArrayExpress

Genevestigator

CLEC4K Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY