All rights reserved

Bio-Magnetic Purification ......   A Powerful Tool for Life Science Research Affinity Magnetic Beads >>> Amine >>                 Aldehyde >>                  Carboxy >>    CDI >>                      DVS >>                          DADPA  >>     Epoxy  >>                 Hydrazide >>                 Hyrdoxy >>     Iodoacetyl >>           NHS >>                         Sulghydry >> Tosyl >>                   Thiol >>                         Silica >> EDTA >>                   IDA >>                      Streptavidin  >> Monomer Avidin >>          Reversed-Phase Magnetic Beads >>> C4 >>                          C8 >>                       C18 >>   Cyanopropyl >>          Phenyl >>                 Dipheny >> Ion Exchange Magnetic Beads >>> DEAE >>                   PSA >>                  SAX >> WCX >>                    SCX >>           Hydroxyapatite  >> Antibody Purification & IP >>> Protein A >>           Protein G >>        Protein A/G >> Protein L >> Recombinant Protein Purification >>> Ni+ Charged Beads >>    Co + Charged Beads >> GST >> DNA & RNA Purification >>> Plant/Animal >>         Bacteria >>             Blood >> Saliva >>                   Stool >>                  Food >> mRNA >>                    PCR >>                   Soil >> Endotoxin Removal Magnetic Beads >>>   Abundant Protein Removal >>> HSA  Removal >>                                    IgG  Removal >> Cell Isolation >>> Bacteria >>                                              Viurs >> More Application >>

Home BioMagnetic Beads Recombinant Protein & Codon Optimized cDNA Service Order Contact Us New Products

For cDNA or Recombinant Protein Search ( Input   Gene name, or Protein Name, or Swiss -prot Accession Number Bioclone Distributor >>>

Email: info@bioclone.us ;  order@bioclone.us

More Than 20,000   Recombinant Protein & cDNA(gene) Virus Antigen  >>> Bacterial Antigen >>> Parasite Antigen  >>> Cell Surface CD Marker >> Cytokines >>> Kinase  >>> Transduction >>> Transcription Factor >>> Common Disease-related Proteins >>> Phosphatase >>> Cancer >>> Drug  metabolism >>> Neuroscience >>> G protein coupled receptors   >>> Stem cell >> Kinase >>> Disease >.>> Toxin & Allergen >>> Cytoskeleton >>

Rat cd184 (extracellular domain fused GFP at C-terminal)

Cmkar4 Swiss Prot#

O08565

Cmkar4 Protein names

C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)

Cmkar4 Gene names

Cxcr4 Cmkar4

Organism

Rat

Cmkar4 Entry name

CXCR4_RAT

Cmkar4 Codon optimized cDNA(gene) Clone

Cmkar4 Cat #

RPV0284

Tag

Cmkar4 contains A 6x histidine tag

Cmkar4 Formulation

Liquid

Cmkar4 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cmkar4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cmkar4 Protein

Cmkar4 Cat #

PV0284

Cmkar4 Source

recombinant.

Cmkar4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cmkar4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cmkar4 Activity

N/A

Tag

Cmkar4 Contains A 6x histidine tag

Cmkar4 Formulation

Liquid

Cmkar4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Place Order for Recombinant Cmkar4 Products

For pricing and availability Click Here >>>

Cmkar4 family

SUBUNIT: Monomer (By similarity). Can form dimers (By similarity). Interacts with CD164. Interacts with ARRB2; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and allows activation of MAPK1 and MAPK3. Interacts with ARRC; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates calcium mobilization. Interacts (via the cytoplasmic C-terminal) with ITCH (via the WW domains I and II); the interaction, enhanced by CXCL12, ubiquitinates CXCR4 and leads to its degradation. Interacts with extracellular ubiquitin; the interaction enhances intracellular calcium ions and reduces cellular cAMP levels (By similarity).

Cmkar4 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity).

Cmkar4 FUNCTION According to UniProtKB Swiss Prot

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival (By similarity).

Cmkar4 Sequence

DDBJ

EMBL

GenBank

Cmkar4 3D structure

ModBase

Cmkar4 interaction

STRING

Cmkar4 Proteomic

PRIDE

Cmkar4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cmkar4 Organism specific

CTD

MGI

Cmkar4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cmkar4 Gene expression

Bgee

ArrayExpress

Genevestigator

Cmkar4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY