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Mouse cd18 (aa 23 – 316)

Itgb2 Swiss Prot#

P11835

Itgb2 Protein names

Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)

Itgb2 Gene names

Itgb2

Organism

Mouse

Itgb2 Entry name

ITB2_MOUSE

Itgb2 Codon optimized cDNA(gene) Clone

Itgb2 Cat #

RPV0268

Tag

Itgb2 contains A 6x histidine tag

Itgb2 Formulation

Liquid

Itgb2 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Itgb2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Itgb2 Protein

Itgb2 Cat #

PV0268

Itgb2 Source

recombinant.

Itgb2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Itgb2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Itgb2 Activity

N/A

Tag

Itgb2 Contains A 6x histidine tag

Itgb2 Formulation

Liquid

Itgb2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Itgb2 family

SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9 (By similarity).

Itgb2 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Itgb2 FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Itgb2 Sequence

DDBJ

EMBL

GenBank

Itgb2 3D structure

ModBase

Itgb2 interaction

STRING

Itgb2 Proteomic

PRIDE

Itgb2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Itgb2 Organism specific

CTD

MGI

Itgb2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Itgb2 Gene expression

Bgee

ArrayExpress

Genevestigator

Itgb2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY