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Mouse CD178 (aa 101 – 279)

Apt1lg1 Swiss Prot#

P41047

Apt1lg1 Protein names

Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form]

Apt1lg1 Gene names

Faslg Apt1lg1 Cd95l Fasl gld Tnfsf6

Organism

Mouse

Apt1lg1 Entry name

TNFL6_MOUSE

Apt1lg1 Codon optimized cDNA(gene) Clone

Apt1lg1 Cat #

RPV0260

Tag

Apt1lg1 contains A 6x histidine tag

Apt1lg1 Formulation

Liquid

Apt1lg1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Apt1lg1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Apt1lg1 Protein

Apt1lg1 Cat #

PV0260

Apt1lg1 Source

recombinant.

Apt1lg1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Apt1lg1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Apt1lg1 Activity

N/A

Tag

Apt1lg1 Contains A 6x histidine tag

Apt1lg1 Formulation

Liquid

Apt1lg1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Apt1lg1 family

SUBUNIT: Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1 (By similarity).

Apt1lg1 Subcellular locations

SUBCELLULAR LOCATION: Isoform FasL: Cell membrane; Single-pass type II membrane protein. ; SUBCELLULAR LOCATION: Isoform FasLS: Secreted. ; SUBCELLULAR LOCATION: Tumor necrosis factor ligand superfamily member 6, soluble form: Secreted.

Apt1lg1 FUNCTION According to UniProtKB Swiss Prot

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity).

Apt1lg1 Sequence

DDBJ

EMBL

GenBank

Apt1lg1 3D structure

ModBase

Apt1lg1 interaction

STRING

Apt1lg1 Proteomic

PRIDE

Apt1lg1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Apt1lg1 Organism specific

CTD

MGI

Apt1lg1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Apt1lg1 Gene expression

Bgee

ArrayExpress

Genevestigator

Apt1lg1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY