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Human cd169 (aa 20 – 405)

SN Swiss Prot#

Q9BZZ2

SN Protein names

Sialoadhesin (Sialic acid-binding Ig-like lectin 1) (Siglec-1) (CD antigen CD169)

SN Gene names

SIGLEC1 SN

Organism

Human

SN Entry name

SN_HUMAN

SN Codon optimized cDNA(gene) Clone

SN Cat #

RPV0242

Tag

SN contains A 6x histidine tag

SN Formulation

Liquid

SN Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SN Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SN Protein

SN Cat #

PV0242

SN Source

recombinant.

SN Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SN Purity

>90%, as determined by SDS-PAGE under reducing conditions

SN Activity

N/A

Tag

SN Contains A 6x histidine tag

SN Formulation

Liquid

SN Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SN family

-

SN Subcellular locations

SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Secreted.

SN FUNCTION According to UniProtKB Swiss Prot

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.

SN Sequence

DDBJ

EMBL

GenBank

SN 3D structure

ModBase

SN interaction

STRING

SN Proteomic

PRIDE

SN Genome annotation

Ensembl

GeneID

KEGG

UCSC

SN Organism specific

CTD

MGI

SN Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SN Gene expression

Bgee

ArrayExpress

Genevestigator

SN Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY