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Mouse cd163 (aa 39-365)

mCG_134311 Swiss Prot#

A6H691

mCG_134311 Protein names

CD163 antigen

mCG_134311 Gene names

Cd163 mCG_134311

Organism

Mouse

mCG_134311 Entry name

A6H691_MOUSE

mCG_134311 Codon optimized cDNA(gene) Clone

mCG_134311 Cat #

RPV0221

Tag

mCG_134311 contains A 6x histidine tag

mCG_134311 Formulation

Liquid

mCG_134311 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

mCG_134311 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant mCG_134311 Protein

mCG_134311 Cat #

PV0221

mCG_134311 Source

recombinant.

mCG_134311 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

mCG_134311 Purity

>90%, as determined by SDS-PAGE under reducing conditions

mCG_134311 Activity

N/A

Tag

mCG_134311 Contains A 6x histidine tag

mCG_134311 Formulation

Liquid

mCG_134311 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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mCG_134311 family

-

mCG_134311 Subcellular locations

-

mCG_134311 FUNCTION According to UniProtKB Swiss Prot

Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.; After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

mCG_134311 Sequence

DDBJ

EMBL

GenBank

mCG_134311 3D structure

ModBase

mCG_134311 interaction

STRING

mCG_134311 Proteomic

PRIDE

mCG_134311 Genome annotation

Ensembl

GeneID

KEGG

UCSC

mCG_134311 Organism specific

CTD

MGI

mCG_134311 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

mCG_134311 Gene expression

Bgee

ArrayExpress

Genevestigator

mCG_134311 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY