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Mouse CD161 (aa 67-214)

Klrb1 Swiss Prot#

F2YRQ5

Klrb1 Protein names

Immunoreceptor NKR-P1G

Klrb1 Gene names

Klrb1

Organism

Mouse

Klrb1 Entry name

F2YRQ5_MOUSE

Klrb1 Codon optimized cDNA(gene) Clone

Klrb1 Cat #

RPV0209

Tag

Klrb1 contains A 6x histidine tag

Klrb1 Formulation

Liquid

Klrb1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Klrb1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Klrb1 Protein

Klrb1 Cat #

PV0209

Klrb1 Source

recombinant.

Klrb1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Klrb1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Klrb1 Activity

N/A

Tag

Klrb1 Contains A 6x histidine tag

Klrb1 Formulation

Liquid

Klrb1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Klrb1 family

-

Klrb1 Subcellular locations

-

Klrb1 FUNCTION According to UniProtKB Swiss Prot

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells

Klrb1 Sequence

DDBJ

EMBL

GenBank

Klrb1 3D structure

ModBase

Klrb1 interaction

STRING

Klrb1 Proteomic

PRIDE

Klrb1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Klrb1 Organism specific

CTD

MGI

Klrb1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Klrb1 Gene expression

Bgee

ArrayExpress

Genevestigator

Klrb1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY