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Mouse cd152 (aa 36 – 161)

Cd152 Swiss Prot#

P09793

Cd152 Protein names

Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)

Cd152 Gene names

Ctla4 Cd152

Organism

Mouse

Cd152 Entry name

CTLA4_MOUSE

Cd152 Codon optimized cDNA(gene) Clone

Cd152 Cat #

RPV0172

Tag

Cd152 contains A 6x histidine tag

Cd152 Formulation

Liquid

Cd152 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cd152 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cd152 Protein

Cd152 Cat #

PV0172

Cd152 Source

recombinant.

Cd152 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cd152 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cd152 Activity

N/A

Tag

Cd152 Contains A 6x histidine tag

Cd152 Formulation

Liquid

Cd152 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cd152 family

SUBUNIT: Homodimer; disulfide-linked. Binds to CD80/B7-1 and CD86/B7.2 (By similarity).

Cd152 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity).

Cd152 FUNCTION According to UniProtKB Swiss Prot

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (By similarity).

Cd152 Sequence

DDBJ

EMBL

GenBank

Cd152 3D structure

ModBase

Cd152 interaction

STRING

Cd152 Proteomic

PRIDE

Cd152 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cd152 Organism specific

CTD

MGI

Cd152 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cd152 Gene expression

Bgee

ArrayExpress

Genevestigator

Cd152 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY