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Human cd150 (aa 21 – 237)

SLAM Swiss Prot#

Q13291

SLAM Protein names

Signaling lymphocytic activation molecule (CDw150) (IPO-3) (CD antigen CD150)

SLAM Gene names

SLAMF1 SLAM

Organism

Human

SLAM Entry name

SLAF1_HUMAN

SLAM Codon optimized cDNA(gene) Clone

SLAM Cat #

RPV0165

Tag

SLAM contains A 6x histidine tag

SLAM Formulation

Liquid

SLAM Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SLAM Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SLAM Protein

SLAM Cat #

PV0165

SLAM Source

recombinant.

SLAM Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SLAM Purity

>90%, as determined by SDS-PAGE under reducing conditions

SLAM Activity

N/A

Tag

SLAM Contains A 6x histidine tag

SLAM Formulation

Liquid

SLAM Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SLAM family

SUBUNIT: Interacts (via cytoplasmic domain) with SH2D1A, and with PTPN11. Interacts with INPP5D/SHIP1. Binds to Measles virus H protein and acts as a receptor for this virus.

SLAM Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells.

SLAM FUNCTION According to UniProtKB Swiss Prot

High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

SLAM Sequence

DDBJ

EMBL

GenBank

SLAM 3D structure

ModBase

SLAM interaction

STRING

SLAM Proteomic

PRIDE

SLAM Genome annotation

Ensembl

GeneID

KEGG

UCSC

SLAM Organism specific

CTD

MGI

SLAM Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SLAM Gene expression

Bgee

ArrayExpress

Genevestigator

SLAM Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY