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Mouse cd141 (aa 17 – 517)

Thbd Swiss Prot#

P15306

Thbd Protein names

Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141)

Thbd Gene names

Thbd

Organism

Mouse

Thbd Entry name

TRBM_MOUSE

Thbd Codon optimized cDNA(gene) Clone

Thbd Cat #

RPV0146

Tag

Thbd contains A 6x histidine tag

Thbd Formulation

Liquid

Thbd Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Thbd Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Thbd Protein

Thbd Cat #

PV0146

Thbd Source

recombinant.

Thbd Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Thbd Purity

>90%, as determined by SDS-PAGE under reducing conditions

Thbd Activity

N/A

Tag

Thbd Contains A 6x histidine tag

Thbd Formulation

Liquid

Thbd Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Thbd family

-

Thbd Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Thbd FUNCTION According to UniProtKB Swiss Prot

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Thbd Sequence

DDBJ

EMBL

GenBank

Thbd 3D structure

ModBase

Thbd interaction

STRING

Thbd Proteomic

PRIDE

Thbd Genome annotation

Ensembl

GeneID

KEGG

UCSC

Thbd Organism specific

CTD

MGI

Thbd Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Thbd Gene expression

Bgee

ArrayExpress

Genevestigator

Thbd Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY