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Human cd141 (aa 19 – 515)

THRM Swiss Prot#

P07204

THRM Protein names

Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141)

THRM Gene names

THBD THRM

Organism

Human

THRM Entry name

TRBM_HUMAN

THRM Codon optimized cDNA(gene) Clone

THRM Cat #

RPV0145

Tag

THRM contains A 6x histidine tag

THRM Formulation

Liquid

THRM Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

THRM Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant THRM Protein

THRM Cat #

PV0145

THRM Source

recombinant.

THRM Applications

Western Blot, SDS-Page or may be used for other applications determined by user

THRM Purity

>90%, as determined by SDS-PAGE under reducing conditions

THRM Activity

N/A

Tag

THRM Contains A 6x histidine tag

THRM Formulation

Liquid

THRM Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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THRM family

-

THRM Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

THRM FUNCTION According to UniProtKB Swiss Prot

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

THRM Sequence

DDBJ

EMBL

GenBank

THRM 3D structure

ModBase

THRM interaction

STRING

THRM Proteomic

PRIDE

THRM Genome annotation

Ensembl

GeneID

KEGG

UCSC

THRM Organism specific

CTD

MGI

THRM Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

THRM Gene expression

Bgee

ArrayExpress

Genevestigator

THRM Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY