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Human cd140b (aa 33 – 531)

PDGFRB Swiss Prot#

P09619

PDGFRB Protein names

Beta-type platelet-derived growth factor receptor (PDGF-R-beta) (EC 2.7.10.1) (CD140 antigen-like family member B) (CD antigen CD140b)

PDGFRB Gene names

PDGFRB

Organism

Human

PDGFRB Entry name

PGFRB_HUMAN

PDGFRB Codon optimized cDNA(gene) Clone

PDGFRB Cat #

RPV0142

Tag

PDGFRB contains A 6x histidine tag

PDGFRB Formulation

Liquid

PDGFRB Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PDGFRB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PDGFRB Protein

PDGFRB Cat #

PV0142

PDGFRB Source

recombinant.

PDGFRB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PDGFRB Purity

>90%, as determined by SDS-PAGE under reducing conditions

PDGFRB Activity

N/A

Tag

PDGFRB Contains A 6x histidine tag

PDGFRB Formulation

Liquid

PDGFRB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PDGFRB family

SUBUNIT: Homodimer, and heterodimer with PDGFRA. Interacts with APS. The autophosphorylated form interacts directly with SHB and with PIK3C2B, maybe indirectly. Interacts with GRB10.

PDGFRB Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

PDGFRB FUNCTION According to UniProtKB Swiss Prot

Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. Phosphorylates Tyr residues at the C-terminus of PTPN11 creating a binding site for the SH2 domain of GRB2.

PDGFRB Sequence

DDBJ

EMBL

GenBank

PDGFRB 3D structure

ModBase

PDGFRB interaction

STRING

PDGFRB Proteomic

PRIDE

PDGFRB Genome annotation

Ensembl

GeneID

KEGG

UCSC

PDGFRB Organism specific

CTD

MGI

PDGFRB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PDGFRB Gene expression

Bgee

ArrayExpress

Genevestigator

PDGFRB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY